Title : Investigation of the In Vitro and In Vivo efficiency of RM-532-105, a 17β-hydroxysteroid dehydrogenase type 3 inhibitor, in LAPC-4 prostate cancer cell and tumor models.

Pub. Date : 2017

PMID : 28182747






1 Functional Relationships(s)
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1 In the fight against androgen-sensitive prostate cancer, the enzyme 17beta-hydroxysteroid dehydrogenase type 3 (17beta-HSD3) is an attractive therapeutic target considering its key role in the formation of androgenic steroids. Steroids hydroxysteroid 11-beta dehydrogenase 1 like Homo sapiens