Title : Plumbagin Prevents IL-1β-Induced Inflammatory Response in Human Osteoarthritis Chondrocytes and Prevents the Progression of Osteoarthritis in Mice.

Pub. Date : 2017 Jun

PMID : 28168658






1 Functional Relationships(s)
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1 We found that plumbagin significantly inhibited the IL-1beta-induced production of NO and PGE2; expression of COX-2, iNOS, MMP-1, MMP-3, and MMP-13; and degradation of aggrecan and collagen-II. Dinoprostone interleukin 1 beta Homo sapiens