Title : Allosteric Mutant IDH1 Inhibitors Reveal Mechanisms for IDH1 Mutant and Isoform Selectivity.

Pub. Date : 2017 Mar 7

PMID : 28132785






1 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 Oncogenic IDH1 and IDH2 mutations contribute to cancer via production of R-2-hydroxyglutarate (2-HG). r-2-hydroxyglutarate isocitrate dehydrogenase (NADP(+)) 1 Homo sapiens