Title : Induction of CFTR gene expression by 1,25(OH)2 vitamin D3, 25OH vitamin D3, and vitamin D3 in cultured human airway epithelial cells and in mouse airways.

Pub. Date : 2017 Oct

PMID : 28130182






1 Functional Relationships(s)
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1 Treatment of BEC with 10muM cholecalciferol led to increases in both CYP24A1 and CFTR mRNA levels, even when added to the apical surface of cells grown in an air-liquid interface, suggesting that topical administration of vitamin D could be used therapeutically. Cholecalciferol cytochrome P450, family 24, subfamily a, polypeptide 1 Mus musculus