Title : Zinc suppresses stem cell properties of lung cancer cells through protein kinase C-mediated β-catenin degradation.

Pub. Date : 2017 Apr 1

PMID : 28122729






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1 Using specific reactive oxygen species detection and antioxidants, we have demonstrated that superoxide anions generated by zinc are a key upstream mechanism for PKCalpha activation leading to the subsequent suppression of stem cell features of lung cancer. Superoxides protein kinase C alpha Homo sapiens