Title : Tumor-associated NADH oxidase (tNOX)-NAD+-sirtuin 1 axis contributes to oxaliplatin-induced apoptosis of gastric cancer cells.

Pub. Date : 2017 Feb 28

PMID : 28122359






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 In AGS cells, we found that the oxaliplatin-inhibited tNOX effectively attenuated the NAD+/NADH ratio and reduced the deacetylase activity of an NAD+-dependent sirtuin 1, thereby enhancing p53 acetylation and apoptosis. Oxaliplatin tumor protein p53 Homo sapiens