Title : Benzofuran-2-acetic ester derivatives induce apoptosis in breast cancer cells by upregulating p21Cip/WAF1 gene expression in p53-independent manner.

Pub. Date : 2017 Mar

PMID : 28108275






1 Functional Relationships(s)
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1 Mechanistically, benzofuran derivatives enhanced the cyclin-dependent kinase inhibitor p21Cip/WAF1 expression at both mRNA and protein levels and this occurs transcriptionally in an Sp1-dependent manner. benzofuran cyclin dependent kinase inhibitor 1A Homo sapiens