Pub. Date : 2017 Feb 21
PMID : 28099144
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | We also find that miR-199a-5p and let-7c increase the sensitivity of HCC cells to sorafenib. | Sorafenib | microRNA let-7c | Homo sapiens |
| 2 | CONCLUSIONS: We report that miR-199a-5p and let-7c cooperatively and efficiently inhibit HCC cell migration and invasion by targeting the metastasis promoter MAP4K3 and MAP4K3-mediated drug sensitization, suggesting that the use of miRNAs and sorafenib in combination therapy may be a powerful approach to the treatment of HCC. | Sorafenib | microRNA let-7c | Homo sapiens |