Title : Cytosolic thioredoxin reductase 1 is required for correct disulfide formation in the ER.

Pub. Date : 2017 Mar 1

PMID : 28093500






1 Functional Relationships(s)
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1 Here, we use a novel assay to demonstrate that the reduction in non-native disulfides requires NADPH as the ultimate electron donor, and a robust cytosolic thioredoxin system, driven by thioredoxin reductase 1 (TrxR1 or TXNRD1). Disulfides thioredoxin Homo sapiens