Title : Quercetin induces apoptosis and autophagy in primary effusion lymphoma cells by inhibiting PI3K/AKT/mTOR and STAT3 signaling pathways.

Pub. Date : 2017 Mar

PMID : 28092744






3 Functional Relationships(s)
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1 Quercetin induces apoptosis and autophagy in primary effusion lymphoma cells by inhibiting PI3K/AKT/mTOR and STAT3 signaling pathways. Quercetin signal transducer and activator of transcription 3 Homo sapiens
2 Quercetin interacts with multiple cancer-related pathways such as PI3K/AKT, Wnt/beta-catenin and STAT3. Quercetin signal transducer and activator of transcription 3 Homo sapiens
3 In this study, we found that quercetin inhibited PI3K/AKT/mTOR and STAT3 pathways in PEL cells, and as a consequence, it down-regulated the expression of the prosurvival cellular proteins such as c-FLIP, cyclin D1 and cMyc. Quercetin signal transducer and activator of transcription 3 Homo sapiens