Pub. Date : 2017 Feb 24
PMID : 28082678
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The Activating C-type Lectin-like Receptor NKp65 Signals through a Hemi-immunoreceptor Tyrosine-based Activation Motif (hemITAM) and Spleen Tyrosine Kinase (Syk). | Tyrosine | killer cell lectin like receptor F2 | Homo sapiens |
| 2 | Previously, we demonstrated that NKp65-mediated cellular cytotoxicity depends on tyrosine 7, located in a cytoplasmic sequence motif of NKp65 resembling a hemi-immunoreceptor tyrosine-based activation motif (hemITAM). | Tyrosine | killer cell lectin like receptor F2 | Homo sapiens |
| 3 | Previously, we demonstrated that NKp65-mediated cellular cytotoxicity depends on tyrosine 7, located in a cytoplasmic sequence motif of NKp65 resembling a hemi-immunoreceptor tyrosine-based activation motif (hemITAM). | Tyrosine | killer cell lectin like receptor F2 | Homo sapiens |
| 4 | We show that NKp65 forms homodimers and is phosphorylated at the hemITAM-embedded tyrosine 7 upon engagement by antibodies or KACL homodimers. | Tyrosine | killer cell lectin like receptor F2 | Homo sapiens |