Title : Wild carrot pentane-based fractions suppress proliferation of human HaCaT keratinocytes and protect against chemically-induced skin cancer.

Pub. Date : 2017 Jan 10

PMID : 28073348






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1 CONCLUSION: The present data reveal that F2 fraction has a remarkable antitumor activity against DMBA/TPA-induced skin carcinogenesis, an effect that may be mediated through inhibition of the MAPK/ERK and PI3K/AKT pathways. Tetradecanoylphorbol Acetate AKT serine/threonine kinase 1 Homo sapiens