Pub. Date : 2017
PMID : 28046007
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | In this paper, we evaluated the impact of 2" sugar moiety substitution for different nucleotides on being substrates for SAMHD1 and mechanisms of actions for the results. | Sugars | SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 | Homo sapiens |
2 | Our computational modeling suggests that (2"S)-2"-methyl sugar moiety clashing with the Y374 of SAMHD1. | Sugars | SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 | Homo sapiens |