Pub. Date : 2017 Jan 17
PMID : 28032592
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Interestingly, lapatinib, a dual EGFR and HER2 tyrosine kinase inhibitor, blocked the increase of cetuximab-induced HER3 phosphorylation. | Lapatinib | erb-b2 receptor tyrosine kinase 3 | Homo sapiens |
| 2 | Additionally, we showed that upon HER3 knockdown, cetuximab combined with lapatinib was able to decrease cell viability compared to HER3 expressing cells. | Lapatinib | erb-b2 receptor tyrosine kinase 3 | Homo sapiens |