Title : Interactions of crizotinib and gefitinib with organic anion-transporting polypeptides (OATP)1B1, OATP1B3 and OATP2B1: gefitinib shows contradictory interaction with OATP1B3.

Pub. Date : 2018 Jan

PMID : 28005438






2 Functional Relationships(s)
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1 Interactions of crizotinib and gefitinib with organic anion-transporting polypeptides (OATP)1B1, OATP1B3 and OATP2B1: gefitinib shows contradictory interaction with OATP1B3. Crizotinib solute carrier organic anion transporter family member 2B1 Homo sapiens
2 OATP1B3- and OATP2B1-mediated crizotinib uptake and OATP2B1-mediated gefitinib uptake were observed. Crizotinib solute carrier organic anion transporter family member 2B1 Homo sapiens