Title : Effects of the regulation of polysialyltransferase ST8SiaII on the invasiveness and metastasis of small cell lung cancer cells.

Pub. Date : 2017 Jan

PMID : 28004110






3 Functional Relationships(s)
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1 In the present study, we analyzed the effects and inherent mechanisms of action of polysialic acid-modified neural cell adhesion molecule (NCAM) on the invasive and metastatic potential of SCLC. polysialic acid neural cell adhesion molecule 1 Homo sapiens
2 In the present study, we analyzed the effects and inherent mechanisms of action of polysialic acid-modified neural cell adhesion molecule (NCAM) on the invasive and metastatic potential of SCLC. polysialic acid neural cell adhesion molecule 1 Homo sapiens
3 Polysialic acid-modified NCAM on the surface of SCLC cells is closely related to the metastatic potential of these cells; regulation of ST8SiaII may thus affect the invasiveness and metastasis of SCLC, and these processes may be associated with phosphorylation of FGFR1, ERK1/2 or MMP-9. polysialic acid neural cell adhesion molecule 1 Homo sapiens