Title : [4Fe-4S] Cluster Assembly in Mitochondria and Its Impairment by Copper.

Pub. Date : 2017 Jan 18

PMID : 27989128






2 Functional Relationships(s)
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1 To describe, from a molecular perspective, the effects of copper(I) toxicity on such a maturation process, we have here investigated the still unknown mechanism of [4Fe-4S] cluster formation conducted by the mitochondrial ISCA1/ISCA2 and GLRX5 proteins, and defined how copper(I) can impair this process. Copper iron-sulfur cluster assembly 1 Homo sapiens
2 To describe, from a molecular perspective, the effects of copper(I) toxicity on such a maturation process, we have here investigated the still unknown mechanism of [4Fe-4S] cluster formation conducted by the mitochondrial ISCA1/ISCA2 and GLRX5 proteins, and defined how copper(I) can impair this process. Copper iron-sulfur cluster assembly 1 Homo sapiens