Title : Hepatocyte autotaxin expression promotes liver fibrosis and cancer.

Pub. Date : 2017 Apr

PMID : 27981605






1 Functional Relationships(s)
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1 In mice, different hepatotoxic stimuli linked with the development of different forms of CLDs were shown to stimulate hepatocyte ATX expression, leading to increased LPA levels, activation of hepatic stellate cells (HSCs), and amplification of profibrotic signals. lysophosphatidic acid ectonucleotide pyrophosphatase/phosphodiesterase 2 Mus musculus