Title : Biomimetic Enantioselective Total Synthesis of (-)-Mycoleptodiscin A.

Pub. Date : 2016 Dec 16

PMID : 27978704






1 Functional Relationships(s)
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1 The crucial step in this synthesis was an intramolecular Friedel-Crafts reaction at C-4 of the indole derivative driven by the EDG/EWG within a compound that was rationally designed to prevent the cyclization reaction at the C-2 positon of indole, thereby successfully providing the complete carbon framework of 1. Carbon complement C4A (Rodgers blood group) Homo sapiens