Title : A Novel Multisensory Integration Task Reveals Robust Deficits in Rodent Models of Schizophrenia: Converging Evidence for Remediation via Nicotinic Receptor Stimulation of Inhibitory Transmission in the Prefrontal Cortex.

Pub. Date : 2016 Dec 14

PMID : 27974613

1 Functional Relationships(s)
Compound Name
Protein Name
1 Orbitofrontal cortex (OFC) administration of nicotine or ABT-418, an alpha4beta2 nicotinic acetylcholine receptor (nAChR) agonist, normalized MSO task performance in ketamine-treated rats and this effect was blocked by GABAA receptor antagonism. Nicotine cholinergic receptor nicotinic beta 1 subunit Rattus norvegicus