Title : Increased activity of TNAP compensates for reduced adenosine production and promotes ectopic calcification in the genetic disease ACDC.

Pub. Date : 2016 Dec 13

PMID : 27965423






1 Functional Relationships(s)
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1 ACDC (arterial calcification due to deficiency of CD73) is an autosomal recessive disease resulting from loss-of-function mutations in NT5E, which encodes CD73, a 5"-ectonucleotidase that converts extracellular adenosine monophosphate to adenosine. Adenosine Monophosphate adiponectin, C1Q and collagen domain containing Homo sapiens