Title : Involvement of high mobility group box-1 in imiquimod-induced psoriasis-like mice model.

Pub. Date : 2017 May

PMID : 27943400






1 Functional Relationships(s)
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1 The injection of HMGB1 into the IMQ-treated skin further aggravated the psoriasis-like disease, enhanced the infiltration of CD3+ T cells, myeloperoxidase+ neutrophils and CD11c+ dendritic cells, increased the number of gammadelta T cells, and upregulated the mRNA expression of interleukin (IL)-6, tumor necrosis factor (TNF)-alpha, interferon (IFN)-gamma and IL-17 compared with the PBS injection. Imiquimod interleukin 17A Homo sapiens