Title : Synergistic disruption of ERα/HER2 crosstalk by endoxifen and lapatinib in breast cancer cells.

Pub. Date : 2017 Jan

PMID : 27942916






3 Functional Relationships(s)
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Protein Name
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1 Synergistic disruption of ERalpha/HER2 crosstalk by endoxifen and lapatinib in breast cancer cells. Lapatinib estrogen receptor 1 Homo sapiens
2 Simultaneous antagonism of ERalpha and HER2 using endoxifen and lapatinib could overcome these problems. Lapatinib estrogen receptor 1 Homo sapiens
3 Synergistic activity was uncovered for lapatinib and endoxifen against BT474, TAM-R and MCF-7/HER2 models of ERalpha/HER2 crosstalk. Lapatinib estrogen receptor 1 Homo sapiens