Title : Molecular mechanism(s) involved in differential expression of vitamin C transporters along the intestinal tract.

Pub. Date : 2017 Apr 1

PMID : 27932501






1 Functional Relationships(s)
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1 These findings show, for the first time, that SVCT-1 and SVCT-2 are differentially expressed along the intestinal tract and that this pattern of expression is, at least in part, mediated via transcriptional/epigenetic mechanisms.NEW & NOTEWORTHY Our findings show, for the first time, that transporters of the water-soluble vitamin ascorbic acid (i.e., the vitamin C transporters SVCT-1 and SVCT-2) are differentially expressed along the length of the intestinal tract and that the pattern of expression is mediated, at least in part, by transcriptional and epigenetic mechanism(s) affecting both Slc23a1 and Slc23a2 genes. Water solute carrier family 23 member 2 Homo sapiens