Title : Herpes Simplex Virus 1 UL41 Protein Suppresses the IRE1/XBP1 Signal Pathway of the Unfolded Protein Response via Its RNase Activity.

Pub. Date : 2017 Feb 15

PMID : 27928013






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Ectopic expression of UL41 decreased the expression of XBP1 and blocked XBP1 splicing activation induced by the ER stress inducer thapsigargin. Thapsigargin X-box binding protein 1 Homo sapiens
2 Wild-type (WT) HSV-1, but not the UL41-null mutant HSV-1 (R2621), decreased XBP1 mRNA induced by thapsigargin. Thapsigargin X-box binding protein 1 Homo sapiens