Title : Inhibition of cystathionine β-synthetase suppresses sodium channel activities of dorsal root ganglion neurons of rats with lumbar disc herniation.

Pub. Date : 2016 Dec 1

PMID : 27905525






3 Functional Relationships(s)
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Protein Name
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1 This study was designed to examine roles of the endogenous hydrogen sulfide synthesizing enzyme cystathionine beta-synthetase (CBS) in sensitization of VGSCs in a previously validated rat model of LDH. Hydrogen Sulfide cystathionine beta synthase Rattus norvegicus
2 This study was designed to examine roles of the endogenous hydrogen sulfide synthesizing enzyme cystathionine beta-synthetase (CBS) in sensitization of VGSCs in a previously validated rat model of LDH. Hydrogen Sulfide cystathionine beta synthase Rattus norvegicus
3 These data suggest that targeting the CBS-H2S signaling at the DRG level might represent a novel therapeutic strategy for chronic pain relief in patients with LDH. Hydrogen Sulfide cystathionine beta synthase Rattus norvegicus