Title : Structures of the Multidrug Transporter P-glycoprotein Reveal Asymmetric ATP Binding and the Mechanism of Polyspecificity.

Pub. Date : 2017 Jan 13

PMID : 27864369






1 Functional Relationships(s)
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1 Despite dramatic reduction in rhodamine 123 and calcein-AM transport, the linker-shortened mutant P-gp possesses basal ATPase activity and binds ATP only in its N-terminal nucleotide-binding domain. Rhodamines phosphoglycolate phosphatase Mus musculus