Pub. Date : 2017 Jan
PMID : 27815364
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Cytochrome P450 2A6 CYP2A6: metabolizes several clinically relevant substrates, including nicotine, the primary psychoactive component in cigarette smoke. | Nicotine | cytochrome P450 family 2 subfamily A member 6 | Homo sapiens |
| 2 | Cytochrome P450 2A6 CYP2A6: metabolizes several clinically relevant substrates, including nicotine, the primary psychoactive component in cigarette smoke. | Nicotine | cytochrome P450 family 2 subfamily A member 6 | Homo sapiens |
| 3 | CYP2A6 enzyme activity was determined through measurement of cotinine formation from nicotine and 7-hydroxycoumarin formation from coumarin. | Nicotine | cytochrome P450 family 2 subfamily A member 6 | Homo sapiens |
| 4 | Overall, several independent and shared sources of variation in CYP2A6 activity in vitro have been identified, which could translate to variable hepatic clearance of nicotine. | Nicotine | cytochrome P450 family 2 subfamily A member 6 | Homo sapiens |