Title : Inhibition of interferon-alpha/beta induction in L-929 cells by benzene and benzene metabolites.

Pub. Date : 1989

PMID : 2779948






2 Functional Relationships(s)
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1 However, exposure of the cells to p-benzoquinone, hydroquinone or catechol, dihydroxy- and diketo-metabolites of benzene, resulted in a severe inhibition of interferon-alpha/beta production. quinone interferon alpha Mus musculus
2 Additional studies with p-benzoquinone indicated that inhibition of interferon-alpha/beta was reversible and could be abrogated by addition of reduced glutathione to the cell cultures. quinone interferon alpha Mus musculus