Title : Human epidermal growth factor receptor 4 (Her4) Suppresses p53 Protein via Targeting the MDMX-MDM2 Protein Complex: IMPLICATION OF A NOVEL MDMX SER-314 PHOSPHOSITE.

Pub. Date : 2016 Dec 9

PMID : 27777309






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Remarkably, inhibition of Ser-314 phosphorylation either with Ser-to-Ala substitution or with a specific inhibitor of CDK4/6 kinase blocked Her4-induced stabilization of MDMX-MDM2 and rescued p53 activity. Alanine tumor protein p53 Homo sapiens