Pub. Date : 2017 Apr 27
PMID : 27775072
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Metformin acts by upregulating microRNA let-7 through AMPK activation, leading to degradation of H19 long noncoding RNA, which normally binds to and inactivates SAHH. | Metformin | H19 imprinted maternally expressed transcript | Homo sapiens |
| 2 | This metformin-induced H19 repression and alteration of gene methylation are recapitulated in endometrial cancer tissue samples obtained from patients treated with antidiabetic doses of metformin. | Metformin | H19 imprinted maternally expressed transcript | Homo sapiens |
| 3 | This metformin-induced H19 repression and alteration of gene methylation are recapitulated in endometrial cancer tissue samples obtained from patients treated with antidiabetic doses of metformin. | Metformin | H19 imprinted maternally expressed transcript | Homo sapiens |