Title : Prophylactic treatment with the tricyclic antidepressant desipramine prevents development of paclitaxel-induced neuropathic pain through activation of endogenous analgesic systems.

Pub. Date : 2016 Dec

PMID : 27773824






1 Functional Relationships(s)
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1 Notably, desipramine (1nM-1muM) alone did not alter tumor cell viability and did not prevent the cytotoxic effects of paclitaxel under identical conditions. Desipramine latexin Homo sapiens