Pub. Date : 2017 Jan
PMID : 27768124
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | The human Tp53 gene harbors a common single-nucleotide polymorphism (SNP) at codon 72, which yields an arginine-to-proline amino-acidic substitution (Arg72Pro) that modulates the apoptotic activity of the p53 protein. | Arginine | tumor protein p53 | Homo sapiens |
2 | The human Tp53 gene harbors a common single-nucleotide polymorphism (SNP) at codon 72, which yields an arginine-to-proline amino-acidic substitution (Arg72Pro) that modulates the apoptotic activity of the p53 protein. | Arginine | tumor protein p53 | Homo sapiens |
3 | Patients harboring the Pro allele of the Tp53 Arg72Pro SNP showed higher levels of circulating EPC-containing CD34+ cells, EPC-mobilizing cytokines - vascular endothelial growth factor and stromal cell-derived factor-1alpha - and good functional outcome following ICH, when compared with the homozygous Arg allele patients, which is compatible with increased neovascularization. | Arginine | tumor protein p53 | Homo sapiens |