Pub. Date : 2017 Jan
PMID : 27750352
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Dynamics of Adrenocorticotropin after Application of Metyrapone. | Metyrapone | proopiomelanocortin | Homo sapiens |
| 2 | Purpose: To investigate the kinetics of adrenocorticotropin (ACTH) following oral metyrapone administration and describe differences between ACTH-deficient and non-ACTH-deficient subjects. | Metyrapone | proopiomelanocortin | Homo sapiens |
| 3 | Purpose: To investigate the kinetics of adrenocorticotropin (ACTH) following oral metyrapone administration and describe differences between ACTH-deficient and non-ACTH-deficient subjects. | Metyrapone | proopiomelanocortin | Homo sapiens |
| 4 | Results: A significant rise in ACTH concentration compared to basal values was found at 60 and 120 min following oral metyrapone administration. | Metyrapone | proopiomelanocortin | Homo sapiens |
| 5 | Conclusion: In contrast to previous reports, we found a significant rise in ACTH concentration as soon as one hour after oral metyrapone administration. | Metyrapone | proopiomelanocortin | Homo sapiens |
| 6 | Further studies are needed to investigate this finding as a potential basis for a ACTH-based metyrapone short test protocol. | Metyrapone | proopiomelanocortin | Homo sapiens |