Pub. Date : 2017 Jun 1
PMID : 27746315
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | TRPA1 mediates changes in heart rate variability and cardiac mechanical function in mice exposed to acrolein. | Acrolein | transient receptor potential cation channel, subfamily A, member 1 | Mus musculus |
| 2 | Thus, this study examines the role of TRPA1, an irritant sensory receptor found in the airways, in the cardiac response of mice to acrolein and ozone. | Acrolein | transient receptor potential cation channel, subfamily A, member 1 | Mus musculus |
| 3 | These data demonstrate that a single exposure to acrolein causes cardiac dysfunction through TRPA1 activation and autonomic imbalance characterized by a shift toward parasympathetic modulation. | Acrolein | transient receptor potential cation channel, subfamily A, member 1 | Mus musculus |