Title : MDA-MB-231 breast cancer cell viability, motility and matrix adhesion are regulated by a complex interplay of heparan sulfate, chondroitin-/dermatan sulfate and hyaluronan biosynthesis.

Pub. Date : 2017 Jun

PMID : 27744520






1 Functional Relationships(s)
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1 Interestingly, EXT1-depleted cells showed a downregulation of the UDP-sugar transporter SLC35D1, whereas SLC35D2 was downregulated in beta4GalT7-depleted cells, indicating an intricate regulatory network that connects all glycosaminoglycans synthesis. Glycosaminoglycans beta-1,4-galactosyltransferase 7 Homo sapiens