Title : Frontline Science: D1 dopaminergic receptor signaling activates the AMPK-bioenergetic pathway in macrophages and alveolar epithelial cells and reduces endotoxin-induced ALI.

Pub. Date : 2017 Feb

PMID : 27733575






1 Functional Relationships(s)
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1 In vivo, fenoldopam reduced the severity of LPS-induced ALI, including development of pulmonary edema, lung permeability, and production of inflammatory cytokines TNF-alpha, MIP-2, or KC and HMGB1. Fenoldopam chemokine (C-X-C motif) ligand 2 Mus musculus