Title : Mammalian Fe-S proteins: definition of a consensus motif recognized by the co-chaperone HSC20.

Pub. Date : 2016 Oct 1

PMID : 27714045






3 Functional Relationships(s)
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1 The delivery of assembled Fe-S clusters to recipient proteins is a crucial step in the biogenesis of Fe-S proteins, and, in mammals, it relies on the activity of a multiprotein transfer complex that contains the chaperone HSPA9, the co-chaperone HSC20 and the scaffold ISCU. Iron HscB mitochondrial iron-sulfur cluster cochaperone Homo sapiens
2 The delivery of assembled Fe-S clusters to recipient proteins is a crucial step in the biogenesis of Fe-S proteins, and, in mammals, it relies on the activity of a multiprotein transfer complex that contains the chaperone HSPA9, the co-chaperone HSC20 and the scaffold ISCU. Iron HscB mitochondrial iron-sulfur cluster cochaperone Homo sapiens
3 This mini review focuses on recent insights into the molecular mechanism of amino acid motif recognition and discrimination by the co-chaperone HSC20, which guides Fe-S cluster delivery. Iron HscB mitochondrial iron-sulfur cluster cochaperone Homo sapiens