Title : HIV-1 Glycan Density Drives the Persistence of the Mannose Patch within an Infected Individual.

Pub. Date : 2016 Dec 15

PMID : 27707925






4 Functional Relationships(s)
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1 Here, using longitudinal Env sequences from a clade C-infected individual (CAP256), we measured the impact of the shifting glycan shield during HIV infection on the abundance of oligomannose-type glycans. Polysaccharides endogenous retrovirus group K member 20 Homo sapiens
2 The HIV envelope glycoprotein (Env) is covered in an array of host-derived N-linked glycans often referred to as the glycan shield. Polysaccharides endogenous retrovirus group K member 20 Homo sapiens
3 The HIV envelope glycoprotein (Env) is covered in an array of host-derived N-linked glycans often referred to as the glycan shield. Polysaccharides endogenous retrovirus group K member 20 Homo sapiens
4 This study aimed to determine whether these genetic changes impacted the eventual processing of glycans on the HIV Env and the susceptibility of the virus to neutralization. Polysaccharides endogenous retrovirus group K member 20 Homo sapiens