Pub. Date : 2017 Apr 15
PMID : 27702817
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The DNA-PK inhibitor, NU7441, induced resistance to rucaparib (P = 0.014) and HR function recovery in a BRCA1-defective cell line.Conclusions: This study has shown that NHEJ is defective in 40% of ovarian cancers, which is independent of HR function and associated with resistance to PARP inhibitors in ex vivo primary cultures. | 8-dibenzothiophen-4-yl-2-morpholin-4-yl-chromen-4-one | collagen type XI alpha 2 chain | Homo sapiens |