CPRiL

5 Functional Relationships(s) Download
	Sentence	Compound Name	Protein Name	Organism
1	INTRODUCTION: The growth factor HBEGF is upregulated post-transcriptionally in the low O2 environment of the human placenta during the first 10 weeks of pregnancy.	Oxygen	heparin binding EGF like growth factor	Homo sapiens
2	We have examined the possible roles of HBEGF turnover and micro-RNA (miRNA) in its regulation by O2 in human first trimester trophoblast.	Oxygen	heparin binding EGF like growth factor	Homo sapiens
3	RESULTS: Protein turnover studies, using 10 mug/ml cyclohexamide, 1 mug/ml lactocystin, or 100 mug/ml MG132, demonstrated faster HBEGF degradation at 20% O2 than 2% O2, mediated by the proteasome.	Oxygen	heparin binding EGF like growth factor	Homo sapiens
4	RESULTS: Protein turnover studies, using 10 mug/ml cyclohexamide, 1 mug/ml lactocystin, or 100 mug/ml MG132, demonstrated faster HBEGF degradation at 20% O2 than 2% O2, mediated by the proteasome.	Oxygen	heparin binding EGF like growth factor	Homo sapiens
5	Nevertheless, HBEGF upregulation at 2% O2 was blocked when the miRNA-processing protein DGCR8 was silenced, suggesting a role for miRNA.	Oxygen	heparin binding EGF like growth factor	Homo sapiens