Title : Black raspberries demethylate Sfrp4, a WNT pathway antagonist, in rat esophageal squamous cell papilloma.

Pub. Date : 2016 Nov

PMID : 27696538






1 Functional Relationships(s)
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1 In addition, promoter methylation of Sfrp4, a WNT pathway antagonist, was significantly reduced by the berry diet, and this was associated with decreased nuclear localization of beta-CATENIN and reduced expression of c-MYC protein in NMBA-treated esophagi. nitrosobenzylmethylamine MYC proto-oncogene, bHLH transcription factor Rattus norvegicus