Title : Enrichment of hydroxylated C24- and C26-acyl-chain sphingolipids mediates PIN2 apical sorting at trans-Golgi network subdomains.

Pub. Date : 2016 Sep 29

PMID : 27681606






3 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Enrichment of hydroxylated C24- and C26-acyl-chain sphingolipids mediates PIN2 apical sorting at trans-Golgi network subdomains. Sphingolipids Auxin efflux carrier family protein Arabidopsis thaliana
2 Here we demonstrate that sphingolipids with alpha-hydroxylated acyl-chains of at least 24 carbon atoms are enriched in secretory vesicle subdomains of the TGN and are critical for de novo polar secretory sorting of the auxin carrier PIN2 to apical membrane of Arabidopsis root epithelial cells. Sphingolipids Auxin efflux carrier family protein Arabidopsis thaliana
3 Our results uncover that the sphingolipids acyl-chain length links lipid composition of TGN subdomains with polar secretory trafficking of PIN2 to apical membrane of polarized epithelial cells. Sphingolipids Auxin efflux carrier family protein Arabidopsis thaliana