Title : Apoptosis May Explain the Pharmacological Mode of Action and Adverse Effects of Isotretinoin, Including Teratogenicity.

Pub. Date : 2017 Feb 8

PMID : 27671426






1 Functional Relationships(s)
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1 Its effect depends on sebocyte apoptosis, which results from isotretinoin-induced expression of the apoptotic protein tumour necrosis factor-related apoptosis-inducing ligand, insulin-like growth factor-binding protein-3 and neutrophil gelatinase-associated lipocalin. Isotretinoin lipocalin 2 Homo sapiens