Title : Inhibition of acetyl-CoA carboxylase suppresses fatty acid synthesis and tumor growth of non-small-cell lung cancer in preclinical models.

Pub. Date : 2016 Oct

PMID : 27643638

1 Functional Relationships(s)
Compound Name
Protein Name
1 We describe the ability of ND-646-an allosteric inhibitor of the ACC enzymes ACC1 and ACC2 that prevents ACC subunit dimerization-to suppress fatty acid synthesis in vitro and in vivo. Fatty Acids acetyl-Coenzyme A carboxylase alpha Mus musculus