Title : A novel approach for targeted delivery to motoneurons using cholera toxin-B modified protocells.

Pub. Date : 2016 Nov 1

PMID : 27641118






2 Functional Relationships(s)
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1 NEW METHOD: We describe a novel delivery system to motoneurons using mesoporous silica nanoparticles encapsulated within a lipid bilayer (protocells) and modified with the atoxic subunit B of the cholera toxin (CTB) that binds to gangliosides present on neuronal membranes. Silicon Dioxide chitobiase Homo sapiens
2 CTB-protocells capitalizes on the advantages of liposomes and mesoporous silica nanoparticles allowing a large loading capacity and cargo release. Silicon Dioxide chitobiase Homo sapiens