Pub. Date : 2016 Nov
PMID : 27624147
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Here, Reynolds and Neill describe the studies that preceded and followed publication of this paper, which reported a deficit in parvalbumin (PV), a calcium-binding protein found in GABA interneurons known to be reduced in schizophrenia patients, in conjunction with a deficit in reversal learning in an animal model for schizophrenia. | gamma-Aminobutyric Acid | parvalbumin | Homo sapiens |
| 2 | Here, Reynolds and Neill describe the studies that preceded and followed publication of this paper, which reported a deficit in parvalbumin (PV), a calcium-binding protein found in GABA interneurons known to be reduced in schizophrenia patients, in conjunction with a deficit in reversal learning in an animal model for schizophrenia. | gamma-Aminobutyric Acid | parvalbumin | Homo sapiens |
| 3 | The hypothesis of a PV deficit came from emerging evidence for a GABAergic dysfunction in schizophrenia, in particular a deficit in PV-containing GABA interneurons. | gamma-Aminobutyric Acid | parvalbumin | Homo sapiens |
| 4 | The latter has included development of a molecule targeting KV3.1 channels located on PV-containing GABA interneurons which can restore both PV expression and cognitive deficits in the scPCP model. | gamma-Aminobutyric Acid | parvalbumin | Homo sapiens |
| 5 | The latter has included development of a molecule targeting KV3.1 channels located on PV-containing GABA interneurons which can restore both PV expression and cognitive deficits in the scPCP model. | gamma-Aminobutyric Acid | parvalbumin | Homo sapiens |