Pub. Date : 2016 Dec
PMID : 27621033
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Quercetin nanoparticles induced autophagy and apoptosis through AKT/ERK/Caspase-3 signaling pathway in human neuroglioma cells: In vitro and in vivo. | Quercetin | caspase 3 | Homo sapiens |
2 | The expression level of LC3 and ERK as well as cytoplasm p53, cleaved Caspase-3 and PARP was positively correlated with the concentration of quercetin nanoparticle. | Quercetin | caspase 3 | Homo sapiens |
3 | These results indicated that quercetin nanoparticle could induce autophagy and apoptosis in human neuroglioma cells, the underlying molecular mechanisms, at least partly, through activation LC3/ERK/Caspase-3 and suppression AKT/mTOR signaling. | Quercetin | caspase 3 | Homo sapiens |