Title : Strain differences in the proteome of dioxin-sensitive and dioxin-resistant mice treated with 2,3,7,8-tetrabromodibenzo-p-dioxin.

Pub. Date : 2017 Apr

PMID : 27604104






1 Functional Relationships(s)
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1 A dose of 10 microg/kg body weight of TBDD induced hepatic CYP1A1 and CYP1A2 expression in both strains, but the expression levels of both CYP1A proteins were higher in C3H/lpr mice than in MRL/lpr mice, supporting that C3H/lpr mice are more sensitive to dioxins than MRL/lpr mice. 2,3,7,8-tetrabromodibenzo-4-dioxin cytochrome P450, family 1, subfamily a, polypeptide 1 Mus musculus