Title : Stimulated release and functional activity of surface expressed metalloproteinase ADAM17 in exosomes.

Pub. Date : 2016 Nov

PMID : 27599715






2 Functional Relationships(s)
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1 We here report that stimulation of lung epithelial A549 tumor cells with phorbol-12-myristate-13-acetate (PMA) leads to the downregulation of the surface expressed mature form of ADAM17 without affecting ADAM10 expression. Tetradecanoylphorbol Acetate ADAM metallopeptidase domain 10 Homo sapiens
2 We here report that stimulation of lung epithelial A549 tumor cells with phorbol-12-myristate-13-acetate (PMA) leads to the downregulation of the surface expressed mature form of ADAM17 without affecting ADAM10 expression. Tetradecanoylphorbol Acetate ADAM metallopeptidase domain 10 Homo sapiens